STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpiA-2Two-component response regulator DpiA; Regulates the expression of citrate fermentation genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)    
Predicted Functional Partners:
AKE09109.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
dpiA
Two-component response regulator DpiA; Regulates the expression of citrate fermentation genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.905
dcuS
Histidine kinase; C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.885
citC
[citrate [pro-3S]-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
 
   
 0.630
citD
Citrate lyase subunit gamma; Covalent carrier of the coenzyme of citrate lyase.
 
   
 0.591
citG
2-(5'-triphosphoribosyl)-3'-dephospho CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.590
citX
2-(5'-triphosphoribosyl)-3'-dephospho CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.588
citF
citrate-ACP transferase, the alpha subunit catalyzes the formation of (3S)-citryl-CoA from acetyl-CoA and citrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.580
citE
Citrate lyase subunit beta; citryl-ACP lyase; catalyzes the formation of acetate and oxaloacetate from citrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
 
     0.530
lacZ
beta-D-galactosidase; Forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.
       0.511
Your Current Organism:
Serratia liquefaciens
NCBI taxonomy Id: 614
Other names: ATCC 27592, Aerobacter liquefaciens, CCUG 9285, CIP 103238, DSM 4487, LMG 7884, LMG:7884, NCTC 12962, S. liquefaciens
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