STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
narXNitrate/nitrite sensor protein NarX; Derived by automated computational analysis using gene prediction method: Protein Homology. (594 aa)    
Predicted Functional Partners:
narL-2
Two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
narL
Nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.968
uhpA
Response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.728
AKE09301.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.712
AKE10009.1
Nitrate/nitrite transporter NarK; Involved in the transport of nitrate and nitrite; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.644
rcsB
Transcriptional regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
 
 
 0.626
AKE08980.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.564
AKE11594.1
feruloyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.564
sirA
Response regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.560
narJ
Delta subunit of nitrate reductase 1; chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.509
Your Current Organism:
Serratia liquefaciens
NCBI taxonomy Id: 614
Other names: ATCC 27592, Aerobacter liquefaciens, CCUG 9285, CIP 103238, DSM 4487, LMG 7884, LMG:7884, NCTC 12962, S. liquefaciens
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