UBE2E3 protein (Rhinopithecus bieti) - STRING interaction network

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UBE2E3

Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)

Predicted Functional Partners:

UBE2E1

0.991

LOC108517237

0.911

GCDH

0.875

UBA1

0.862

TRIP12

0.850

BRCA1

0.784

RNF25

0.779

RNF5

0.779

ENSRBIP00000020891

0.766

ENSRBIP00000014363

0.760

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA1	LOC108517237	ENSRBIP00000041182	ENSRBIP00000018755	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Uncharacterized protein.	0.816
BRCA1	UBE2E1	ENSRBIP00000041182	ENSRBIP00000020617	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family.	0.829
BRCA1	UBE2E3	ENSRBIP00000041182	ENSRBIP00000002012	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family.	0.784
ENSRBIP00000014363	ENSRBIP00000020891	ENSRBIP00000014363	ENSRBIP00000020891	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.810
ENSRBIP00000014363	LOC108517237	ENSRBIP00000014363	ENSRBIP00000018755	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.760
ENSRBIP00000014363	TRIP12	ENSRBIP00000014363	ENSRBIP00000037272	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Thyroid hormone receptor interactor 12.	0.406
ENSRBIP00000014363	UBA1	ENSRBIP00000014363	ENSRBIP00000020121	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.624
ENSRBIP00000014363	UBE2E1	ENSRBIP00000014363	ENSRBIP00000020617	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family.	0.760
ENSRBIP00000014363	UBE2E3	ENSRBIP00000014363	ENSRBIP00000002012	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family.	0.760
ENSRBIP00000020891	ENSRBIP00000014363	ENSRBIP00000020891	ENSRBIP00000014363	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.810
ENSRBIP00000020891	LOC108517237	ENSRBIP00000020891	ENSRBIP00000018755	Uncharacterized protein.	Uncharacterized protein.	0.766
ENSRBIP00000020891	TRIP12	ENSRBIP00000020891	ENSRBIP00000037272	Uncharacterized protein.	Thyroid hormone receptor interactor 12.	0.406
ENSRBIP00000020891	UBA1	ENSRBIP00000020891	ENSRBIP00000020121	Uncharacterized protein.	Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.	0.652
ENSRBIP00000020891	UBE2E1	ENSRBIP00000020891	ENSRBIP00000020617	Uncharacterized protein.	Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family.	0.766
ENSRBIP00000020891	UBE2E3	ENSRBIP00000020891	ENSRBIP00000002012	Uncharacterized protein.	Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family.	0.766
GCDH	UBE2E3	ENSRBIP00000014478	ENSRBIP00000002012	Glutaryl-CoA dehydrogenase.	Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family.	0.875
LOC108517237	BRCA1	ENSRBIP00000018755	ENSRBIP00000041182	Uncharacterized protein.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.816
LOC108517237	ENSRBIP00000014363	ENSRBIP00000018755	ENSRBIP00000014363	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.760
LOC108517237	ENSRBIP00000020891	ENSRBIP00000018755	ENSRBIP00000020891	Uncharacterized protein.	Uncharacterized protein.	0.766
LOC108517237	RNF25	ENSRBIP00000018755	ENSRBIP00000015105	Uncharacterized protein.	Ring finger protein 25.	0.623