STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa)    
Predicted Functional Partners:
SIX1
SIX homeobox 1.
   
 
 0.614
GJB2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.583
SIX4
SIX homeobox 4.
   
 
 0.581
SIX5
SIX homeobox 5.
   
 
 0.576
SIX2
SIX homeobox 2.
   
 
 0.576
SIX6
SIX homeobox 6.
   
 
 0.529
SIX3
SIX homeobox 3.
   
 
 0.529
ANHX
Anomalous homeobox.
   
 
 0.529
KCNQ4
Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family.
      
 0.512
PAX8
Paired box 8.
      
 0.448
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.