STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZFHX3Zinc finger homeobox 3. (3662 aa)    
Predicted Functional Partners:
RUNX2
RUNX family transcription factor 2.
     
 0.907
MED12
Mediator complex subunit 12.
      
 0.874
KCNN3
Potassium calcium-activated channel subfamily N member 3.
      
 0.836
RUNX1
RUNX family transcription factor 1.
     
 0.771
ATXN7
SCA7 domain-containing protein.
      
 0.699
PAXIP1
PAX interacting protein 1.
      
 0.698
TBP
TATA-box binding protein.
      
 0.685
RUNX3
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
     
 0.677
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
    
  0.675
KMT2D
Lysine methyltransferase 2D.
   
  
 0.658
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (10%) [HD]