node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC6 | ENSRBIP00000014998 | ENSRBIP00000037371 | ENSRBIP00000014998 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.784 |
CDC6 | MCM2 | ENSRBIP00000037371 | ENSRBIP00000020818 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC6 | MCM3 | ENSRBIP00000037371 | ENSRBIP00000024938 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC6 | MCM4 | ENSRBIP00000037371 | ENSRBIP00000027818 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC6 | MCM5 | ENSRBIP00000037371 | ENSRBIP00000023013 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC6 | MCM6 | ENSRBIP00000037371 | ENSRBIP00000029219 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC6 | MCM7 | ENSRBIP00000037371 | ENSRBIP00000017365 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
CDC6 | ORC2 | ENSRBIP00000037371 | ENSRBIP00000018290 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 2. | 0.999 |
CDC6 | ORC4 | ENSRBIP00000037371 | ENSRBIP00000029391 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.999 |
CDC6 | ORC5 | ENSRBIP00000037371 | ENSRBIP00000027852 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 5. | 0.999 |
ENSRBIP00000014998 | CDC6 | ENSRBIP00000014998 | ENSRBIP00000037371 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.784 |
ENSRBIP00000014998 | MCM2 | ENSRBIP00000014998 | ENSRBIP00000020818 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | DNA helicase; Belongs to the MCM family. | 0.784 |
ENSRBIP00000014998 | MCM3 | ENSRBIP00000014998 | ENSRBIP00000024938 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | DNA helicase; Belongs to the MCM family. | 0.780 |
ENSRBIP00000014998 | MCM4 | ENSRBIP00000014998 | ENSRBIP00000027818 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | DNA helicase; Belongs to the MCM family. | 0.780 |
ENSRBIP00000014998 | MCM5 | ENSRBIP00000014998 | ENSRBIP00000023013 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | DNA helicase; Belongs to the MCM family. | 0.780 |
ENSRBIP00000014998 | MCM6 | ENSRBIP00000014998 | ENSRBIP00000029219 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | DNA helicase; Belongs to the MCM family. | 0.780 |
ENSRBIP00000014998 | MCM7 | ENSRBIP00000014998 | ENSRBIP00000017365 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.780 |
ENSRBIP00000014998 | ORC2 | ENSRBIP00000014998 | ENSRBIP00000018290 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Origin recognition complex subunit 2. | 0.780 |
ENSRBIP00000014998 | ORC4 | ENSRBIP00000014998 | ENSRBIP00000029391 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.780 |
ENSRBIP00000014998 | ORC5 | ENSRBIP00000014998 | ENSRBIP00000027852 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Origin recognition complex subunit 5. | 0.780 |