node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CGA | FSHR | ENSRBIP00000019574 | ENSRBIP00000019852 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.929 |
CGA | LHB | ENSRBIP00000019574 | ENSRBIP00000034032 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Cys_knot domain-containing protein. | 0.862 |
CGA | LHCGR | ENSRBIP00000019574 | ENSRBIP00000010073 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.738 |
CGA | POMC | ENSRBIP00000019574 | ENSRBIP00000002977 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Proopiomelanocortin. | 0.798 |
CGA | TSHR | ENSRBIP00000019574 | ENSRBIP00000033138 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.887 |
ENSRBIP00000008844 | LHB | ENSRBIP00000008844 | ENSRBIP00000034032 | NTF2 domain-containing protein. | Cys_knot domain-containing protein. | 0.501 |
ENSRBIP00000010861 | LHB | ENSRBIP00000010861 | ENSRBIP00000034032 | NTF2 domain-containing protein. | Cys_knot domain-containing protein. | 0.501 |
FANCA | LHB | ENSRBIP00000005614 | ENSRBIP00000034032 | FA complementation group A. | Cys_knot domain-containing protein. | 0.501 |
FOS | LHB | ENSRBIP00000024863 | ENSRBIP00000034032 | Fos proto-oncogene, AP-1 transcription factor subunit. | Cys_knot domain-containing protein. | 0.400 |
FOS | POMC | ENSRBIP00000024863 | ENSRBIP00000002977 | Fos proto-oncogene, AP-1 transcription factor subunit. | Proopiomelanocortin. | 0.557 |
FSHR | CGA | ENSRBIP00000019852 | ENSRBIP00000019574 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.929 |
FSHR | LHB | ENSRBIP00000019852 | ENSRBIP00000034032 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Cys_knot domain-containing protein. | 0.451 |
LHB | CGA | ENSRBIP00000034032 | ENSRBIP00000019574 | Cys_knot domain-containing protein. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.862 |
LHB | ENSRBIP00000008844 | ENSRBIP00000034032 | ENSRBIP00000008844 | Cys_knot domain-containing protein. | NTF2 domain-containing protein. | 0.501 |
LHB | ENSRBIP00000010861 | ENSRBIP00000034032 | ENSRBIP00000010861 | Cys_knot domain-containing protein. | NTF2 domain-containing protein. | 0.501 |
LHB | FANCA | ENSRBIP00000034032 | ENSRBIP00000005614 | Cys_knot domain-containing protein. | FA complementation group A. | 0.501 |
LHB | FOS | ENSRBIP00000034032 | ENSRBIP00000024863 | Cys_knot domain-containing protein. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.400 |
LHB | FSHR | ENSRBIP00000034032 | ENSRBIP00000019852 | Cys_knot domain-containing protein. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.451 |
LHB | LHCGR | ENSRBIP00000034032 | ENSRBIP00000010073 | Cys_knot domain-containing protein. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.593 |
LHB | NUTF2 | ENSRBIP00000034032 | ENSRBIP00000005140 | Cys_knot domain-containing protein. | NTF2 domain-containing protein. | 0.501 |