STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)    
Predicted Functional Partners:
GTF2A1
General transcription factor IIA subunit 1.
    
 0.997
GTF2B
General transcription factor IIB.
   
 0.971
GTF2E1
General transcription factor IIE subunit 1.
    
 0.970
GTF2E2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
   
 0.961
GTF2H3
General transcription factor IIH subunit 3.
    
 0.959
TBP
TATA-box binding protein.
   
 0.955
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
    
 0.948
GTF2H2
C2H2-type domain-containing protein.
   
 0.948
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
    
 0.942
POLR2H
RNA polymerase II subunit H.
    
 0.940
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.