STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)    
Predicted Functional Partners:
KPNB1
Karyopherin subunit beta 1.
   
 0.974
CSE1L
Chromosome segregation 1 like.
   
 0.972
KPNA3
Importin subunit alpha; Functions in nuclear protein import.
  
0.948
KPNA4
Importin subunit alpha; Functions in nuclear protein import.
  
0.942
RELA
RELA proto-oncogene, NF-kB subunit.
    
 0.923
STAT1
Signal transducer and activator of transcription.
    
 0.913
NFKB1
Nuclear factor kappa B subunit 1.
    
 0.908
NUP50
Nucleoporin 50.
   
 
 0.894
TERT
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]
   
 
 0.773
RCC1
Regulator of chromosome condensation 1.
   
 
 0.743
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.