node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APAF1 | CASP9 | ENSRROP00000022100 | ENSRROP00000036378 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Caspase 9; Belongs to the peptidase C14A family. | 0.999 |
APAF1 | NFE2L2 | ENSRROP00000022100 | ENSRROP00000044750 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Nuclear factor, erythroid 2 like 2. | 0.593 |
APAF1 | NFE2L3 | ENSRROP00000022100 | ENSRROP00000014061 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Nuclear factor, erythroid 2 like 3. | 0.586 |
APAF1 | OSBPL3 | ENSRROP00000022100 | ENSRROP00000006193 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Oxysterol-binding protein; Belongs to the OSBP family. | 0.660 |
APAF1 | PDE11A | ENSRROP00000022100 | ENSRROP00000008741 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | Phosphodiesterase. | 0.579 |
CASP9 | APAF1 | ENSRROP00000036378 | ENSRROP00000022100 | Caspase 9; Belongs to the peptidase C14A family. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.999 |
CASP9 | NFE2L3 | ENSRROP00000036378 | ENSRROP00000014061 | Caspase 9; Belongs to the peptidase C14A family. | Nuclear factor, erythroid 2 like 3. | 0.576 |
CASP9 | OSBPL3 | ENSRROP00000036378 | ENSRROP00000006193 | Caspase 9; Belongs to the peptidase C14A family. | Oxysterol-binding protein; Belongs to the OSBP family. | 0.580 |
CASP9 | PDE11A | ENSRROP00000036378 | ENSRROP00000008741 | Caspase 9; Belongs to the peptidase C14A family. | Phosphodiesterase. | 0.567 |
ENSRROP00000012180 | OSBPL3 | ENSRROP00000012180 | ENSRROP00000006193 | MSP domain-containing protein. | Oxysterol-binding protein; Belongs to the OSBP family. | 0.630 |
ENSRROP00000012180 | VAPB | ENSRROP00000012180 | ENSRROP00000022712 | MSP domain-containing protein. | VAMP associated protein B and C. | 0.682 |
LRIG2 | OSBPL3 | ENSRROP00000045054 | ENSRROP00000006193 | Leucine rich repeats and immunoglobulin like domains 2. | Oxysterol-binding protein; Belongs to the OSBP family. | 0.570 |
NFE2L2 | APAF1 | ENSRROP00000044750 | ENSRROP00000022100 | Nuclear factor, erythroid 2 like 2. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.593 |
NFE2L2 | OSBPL3 | ENSRROP00000044750 | ENSRROP00000006193 | Nuclear factor, erythroid 2 like 2. | Oxysterol-binding protein; Belongs to the OSBP family. | 0.736 |
NFE2L2 | PDE11A | ENSRROP00000044750 | ENSRROP00000008741 | Nuclear factor, erythroid 2 like 2. | Phosphodiesterase. | 0.578 |
NFE2L3 | APAF1 | ENSRROP00000014061 | ENSRROP00000022100 | Nuclear factor, erythroid 2 like 3. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.586 |
NFE2L3 | CASP9 | ENSRROP00000014061 | ENSRROP00000036378 | Nuclear factor, erythroid 2 like 3. | Caspase 9; Belongs to the peptidase C14A family. | 0.576 |
NFE2L3 | OSBPL3 | ENSRROP00000014061 | ENSRROP00000006193 | Nuclear factor, erythroid 2 like 3. | Oxysterol-binding protein; Belongs to the OSBP family. | 0.578 |
NFE2L3 | PDE11A | ENSRROP00000014061 | ENSRROP00000008741 | Nuclear factor, erythroid 2 like 3. | Phosphodiesterase. | 0.615 |
OSBPL3 | APAF1 | ENSRROP00000006193 | ENSRROP00000022100 | Oxysterol-binding protein; Belongs to the OSBP family. | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. | 0.660 |