HGF protein (Rhinopithecus roxellana) - STRING interaction network

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HGF

Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)

Predicted Functional Partners:

MET

0.999

MST1R

0.954

SPINT1

0.934

ERBB3

0.926

STAT3

0.910

SPINT2

0.909

HPN

0.883

GAB1

0.867

PIK3CA

0.835

HGFAC

0.829

Your Current Organism:

Rhinopithecus roxellana

NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERBB3	GAB1	ENSRROP00000010976	ENSRROP00000011471	Erb-b2 receptor tyrosine kinase 3.	GRB2 associated binding protein 1.	0.977
ERBB3	HGF	ENSRROP00000010976	ENSRROP00000008564	Erb-b2 receptor tyrosine kinase 3.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.926
ERBB3	MET	ENSRROP00000010976	ENSRROP00000038319	Erb-b2 receptor tyrosine kinase 3.	MET proto-oncogene, receptor tyrosine kinase.	0.974
ERBB3	MST1R	ENSRROP00000010976	ENSRROP00000026718	Erb-b2 receptor tyrosine kinase 3.	Macrophage stimulating 1 receptor.	0.703
ERBB3	PIK3CA	ENSRROP00000010976	ENSRROP00000011898	Erb-b2 receptor tyrosine kinase 3.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.992
ERBB3	STAT3	ENSRROP00000010976	ENSRROP00000018412	Erb-b2 receptor tyrosine kinase 3.	Signal transducer and activator of transcription.	0.735
GAB1	ERBB3	ENSRROP00000011471	ENSRROP00000010976	GRB2 associated binding protein 1.	Erb-b2 receptor tyrosine kinase 3.	0.977
GAB1	HGF	ENSRROP00000011471	ENSRROP00000008564	GRB2 associated binding protein 1.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.867
GAB1	HGFAC	ENSRROP00000011471	ENSRROP00000030714	GRB2 associated binding protein 1.	HGF activator.	0.478
GAB1	MET	ENSRROP00000011471	ENSRROP00000038319	GRB2 associated binding protein 1.	MET proto-oncogene, receptor tyrosine kinase.	0.991
GAB1	MST1R	ENSRROP00000011471	ENSRROP00000026718	GRB2 associated binding protein 1.	Macrophage stimulating 1 receptor.	0.885
GAB1	PIK3CA	ENSRROP00000011471	ENSRROP00000011898	GRB2 associated binding protein 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.979
HGF	ERBB3	ENSRROP00000008564	ENSRROP00000010976	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Erb-b2 receptor tyrosine kinase 3.	0.926
HGF	GAB1	ENSRROP00000008564	ENSRROP00000011471	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	GRB2 associated binding protein 1.	0.867
HGF	HGFAC	ENSRROP00000008564	ENSRROP00000030714	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	HGF activator.	0.829
HGF	HPN	ENSRROP00000008564	ENSRROP00000016937	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepsin; Belongs to the peptidase S1 family.	0.883
HGF	MET	ENSRROP00000008564	ENSRROP00000038319	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	MET proto-oncogene, receptor tyrosine kinase.	0.999
HGF	MST1R	ENSRROP00000008564	ENSRROP00000026718	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Macrophage stimulating 1 receptor.	0.954
HGF	PIK3CA	ENSRROP00000008564	ENSRROP00000011898	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.835
HGF	SPINT1	ENSRROP00000008564	ENSRROP00000017186	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Serine peptidase inhibitor, Kunitz type 1.	0.934

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