STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRVI1Murine retrovirus integration site 1 homolog. (911 aa)    
Predicted Functional Partners:
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
    
 0.986
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
    
 0.976
PRKG1
Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily.
   
 0.970
PRKG2
cGMP-dependent protein kinase.
   
 0.966
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
    
 0.964
MED4-2
Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.714
LRRC3B
Leucine rich repeat containing 3B.
    
 0.674
PEAR1
Platelet endothelial aggregation receptor 1.
     
 0.577
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.570
STOX1
Storkhead box 1.
      
 0.568
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.