Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
mutSDNA mismatch repair protein MutS, truncated. (221 aa)    
Predicted Functional Partners:
mutS-2
DNA mismatch repair protein MutS, truncated; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
     0.994
fbpA
Fibronectin-binding protein A.
 
   
 0.759
rnhC
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.582
trx
Thioredoxin; Belongs to the thioredoxin family.
       0.573
dacA
Conserved hypothetical membrane-anchored protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
 
     0.530
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
   0.484
rpmI
50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
   
   0.422
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.422
rpmB
50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
   
   0.407
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
   0.407
Your Current Organism:
Acholeplasma brassicae
NCBI taxonomy Id: 61635
Other names: A. brassicae, ATCC 49388, strain 0502
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