node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BN85312190 | BN85312230 | BN85312190 | BN85312230 | Major facilitator superfamily transporter. | Phospholipid/glycerol acyltransferase domain. | 0.588 |
BN85312190 | mnmA | BN85312190 | BN85312200 | Major facilitator superfamily transporter. | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.777 |
BN85312190 | nadD | BN85312190 | BN85312220 | Major facilitator superfamily transporter. | Nicotinate-nucleotide adenylyltransferase; Belongs to the NadD family. | 0.774 |
BN85312190 | nadE | BN85312190 | BN85312210 | Major facilitator superfamily transporter. | NAD(+) synthase, glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.797 |
BN85312190 | recD | BN85312190 | BN85312180 | Major facilitator superfamily transporter. | ATP-dependent exoDNAse (Exonuclease V), alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.793 |
BN85312230 | BN85312190 | BN85312230 | BN85312190 | Phospholipid/glycerol acyltransferase domain. | Major facilitator superfamily transporter. | 0.588 |
BN85312230 | mnmA | BN85312230 | BN85312200 | Phospholipid/glycerol acyltransferase domain. | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.564 |
BN85312230 | nadD | BN85312230 | BN85312220 | Phospholipid/glycerol acyltransferase domain. | Nicotinate-nucleotide adenylyltransferase; Belongs to the NadD family. | 0.568 |
BN85312230 | nadE | BN85312230 | BN85312210 | Phospholipid/glycerol acyltransferase domain. | NAD(+) synthase, glutamine-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.669 |
BN85312230 | recD | BN85312230 | BN85312180 | Phospholipid/glycerol acyltransferase domain. | ATP-dependent exoDNAse (Exonuclease V), alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.551 |
BN85314530 | dnaN | BN85314530 | BN85300020 | Predicted DNA helicase (ATP-dependent, RecQ type). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.672 |
BN85314530 | recD | BN85314530 | BN85312180 | Predicted DNA helicase (ATP-dependent, RecQ type). | ATP-dependent exoDNAse (Exonuclease V), alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.648 |
BN85314530 | topA | BN85314530 | BN85306350 | Predicted DNA helicase (ATP-dependent, RecQ type). | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.998 |
addA | recD | BN85300200 | BN85312180 | ATP-dependent helicase/nuclease subunit A. | ATP-dependent exoDNAse (Exonuclease V), alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.779 |
addA | topA | BN85300200 | BN85306350 | ATP-dependent helicase/nuclease subunit A. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.467 |
dnaN | BN85314530 | BN85300020 | BN85314530 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Predicted DNA helicase (ATP-dependent, RecQ type). | 0.672 |
dnaN | recD | BN85300020 | BN85312180 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent exoDNAse (Exonuclease V), alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.823 |
dnaN | topA | BN85300020 | BN85306350 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.595 |
mnmA | BN85312190 | BN85312200 | BN85312190 | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Major facilitator superfamily transporter. | 0.777 |
mnmA | BN85312230 | BN85312200 | BN85312230 | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | Phospholipid/glycerol acyltransferase domain. | 0.564 |