STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdBRibonucleoside-diphosphate reductase, beta subunit. (390 aa)    
Predicted Functional Partners:
nrdA
Ribonucleoside-diphosphate reductase, alpha subunit.
 
 0.999
nrdE
Ribonucleoside-diphosphate reductase, alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.995
tmk
Thymidylate kinase (dTMP kinase); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.939
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.932
pykF-2
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.932
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.911
BN85310690
Similar to guanylate kinase.
     
 0.911
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.909
spoT
Guanosine polyphosphate pyrophosphohydrolase/synthetase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.907
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
  
  
 0.747
Your Current Organism:
Acholeplasma brassicae
NCBI taxonomy Id: 61635
Other names: A. brassicae, ATCC 49388, strain 0502
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.