node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANG91102.1 | ANG91134.1 | A8A57_01345 | A8A57_01515 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
ANG91102.1 | ANG91674.1 | A8A57_01345 | A8A57_04405 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
ANG91102.1 | ANG92822.1 | A8A57_01345 | A8A57_10575 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
ANG91102.1 | ANG93174.1 | A8A57_01345 | A8A57_12495 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Free methionine-R-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
ANG91102.1 | ANG94176.1 | A8A57_01345 | A8A57_17910 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
ANG91102.1 | ANG94755.1 | A8A57_01345 | A8A57_21035 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
ANG91102.1 | luxS | A8A57_01345 | A8A57_16355 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.930 |
ANG91102.1 | metE | A8A57_01345 | A8A57_20645 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.920 |
ANG91102.1 | metK | A8A57_01345 | A8A57_17460 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.938 |
ANG91134.1 | ANG91102.1 | A8A57_01515 | A8A57_01345 | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.900 |
ANG91134.1 | ANG91674.1 | A8A57_01515 | A8A57_04405 | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.905 |
ANG91134.1 | ANG92822.1 | A8A57_01515 | A8A57_10575 | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
ANG91134.1 | ANG93174.1 | A8A57_01515 | A8A57_12495 | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Free methionine-R-sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
ANG91134.1 | metE | A8A57_01515 | A8A57_20645 | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.903 |
ANG91134.1 | metK | A8A57_01515 | A8A57_17460 | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.907 |
ANG91673.1 | ANG91674.1 | A8A57_04400 | A8A57_04405 | Amino acid transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
ANG91674.1 | ANG91102.1 | A8A57_04405 | A8A57_01345 | Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.924 |
ANG91674.1 | ANG91134.1 | A8A57_04405 | A8A57_01515 | Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.905 |
ANG91674.1 | ANG91673.1 | A8A57_04405 | A8A57_04400 | Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amino acid transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
ANG91674.1 | ANG92822.1 | A8A57_04405 | A8A57_10575 | Homocysteine S-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |