node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANG92587.1 | ANG93747.1 | A8A57_09300 | A8A57_15600 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.425 |
ANG92587.1 | ANG93752.1 | A8A57_09300 | A8A57_15625 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.795 |
ANG92587.1 | fdx | A8A57_09300 | A8A57_15605 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.737 |
ANG92587.1 | hscA | A8A57_09300 | A8A57_15610 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.505 |
ANG92587.1 | hscB | A8A57_09300 | A8A57_15615 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.824 |
ANG92587.1 | iscR | A8A57_09300 | A8A57_15635 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.605 |
ANG92587.1 | iscS | A8A57_09300 | A8A57_15630 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.844 |
ANG92587.1 | nfuA | A8A57_09300 | A8A57_19910 | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.540 |
ANG92913.1 | ANG93752.1 | A8A57_11065 | A8A57_15625 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.446 |
ANG92913.1 | iscR | A8A57_11065 | A8A57_15635 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.535 |
ANG92913.1 | iscS | A8A57_11065 | A8A57_15630 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.652 |
ANG92913.1 | nfuA | A8A57_11065 | A8A57_19910 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.641 |
ANG93747.1 | ANG92587.1 | A8A57_15600 | A8A57_09300 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold SufA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. | 0.425 |
ANG93747.1 | ANG93752.1 | A8A57_15600 | A8A57_15625 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.928 |
ANG93747.1 | fdx | A8A57_15600 | A8A57_15605 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
ANG93747.1 | hscA | A8A57_15600 | A8A57_15610 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. | 0.961 |
ANG93747.1 | hscB | A8A57_15600 | A8A57_15615 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.983 |
ANG93747.1 | iscA | A8A57_15600 | A8A57_15620 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. | 0.863 |
ANG93747.1 | iscR | A8A57_15600 | A8A57_15635 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.584 |
ANG93747.1 | iscS | A8A57_15600 | A8A57_15630 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.885 |