node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANG93911.1 | ANG93916.1 | A8A57_16500 | A8A57_16525 | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.465 |
ANG93911.1 | ANG93926.1 | A8A57_16500 | A8A57_16575 | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase accessory protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.827 |
ANG93911.1 | ANG93927.1 | A8A57_16500 | A8A57_16580 | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase assembly chaperone; HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.894 |
ANG93911.1 | ANG93928.1 | A8A57_16500 | A8A57_16585 | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase formation protein HypD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | 0.895 |
ANG93911.1 | ANG93929.1 | A8A57_16500 | A8A57_16590 | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase expression/formation protein HypE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.983 |
ANG93911.1 | hycE | A8A57_16500 | A8A57_16545 | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.657 |
ANG93911.1 | hypA | A8A57_16500 | A8A57_16570 | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.859 |
ANG93916.1 | ANG93911.1 | A8A57_16525 | A8A57_16500 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.465 |
ANG93916.1 | ANG93923.1 | A8A57_16525 | A8A57_16560 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.796 |
ANG93916.1 | ANG93924.1 | A8A57_16525 | A8A57_16565 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.481 |
ANG93916.1 | ANG93926.1 | A8A57_16525 | A8A57_16575 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase accessory protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.455 |
ANG93916.1 | ANG93927.1 | A8A57_16525 | A8A57_16580 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase assembly chaperone; HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.570 |
ANG93916.1 | ANG93928.1 | A8A57_16525 | A8A57_16585 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase formation protein HypD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | 0.551 |
ANG93916.1 | ANG93929.1 | A8A57_16525 | A8A57_16590 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase expression/formation protein HypE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.581 |
ANG93916.1 | hycE | A8A57_16525 | A8A57_16545 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.941 |
ANG93916.1 | hypA | A8A57_16525 | A8A57_16570 | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.611 |
ANG93923.1 | ANG93916.1 | A8A57_16560 | A8A57_16525 | Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase maturation peptidase HycI; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.796 |
ANG93923.1 | ANG93924.1 | A8A57_16560 | A8A57_16565 | Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.878 |
ANG93923.1 | ANG93926.1 | A8A57_16560 | A8A57_16575 | Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase accessory protein HypB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
ANG93923.1 | ANG93929.1 | A8A57_16560 | A8A57_16590 | Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase expression/formation protein HypE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.479 |