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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIQ99025.1Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)    
Predicted Functional Partners:
LG71_06910
DNA methyltransferase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.910
AIQ99868.1
DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.910
topA_2
DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...]
  
 
 0.910
AIQ99415.1
ssDNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
     
  0.900
AIQ99640.1
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
AIQ99870.1
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.829
AMR39175.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
AIQ99026.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.741
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 
 0.722
Your Current Organism:
Pluralibacter gergoviae
NCBI taxonomy Id: 61647
Other names: ATCC 33028, CCUG 14557, CDC 604-77, CIP 76.01, CIP 76.1, DSM 9245, Enterobacter gergoviae, Enterobacter gergoviensis, LMG 5739, LMG:5739, NBRC 105706, NCTC 11434, P. gergoviae
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