STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIQ99509.2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)    
Predicted Functional Partners:
AIQ99510.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.969
rcsD
Phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
   
 0.958
AIR00099.1
Hybrid sensor histidine kinase/response regulator; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.926
rcsB_2
DNA-binding response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
  
  
 
0.926
rcsA
Helix-turn-helix transcriptional regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.
  
 0.842
AIQ98613.1
Aerobic respiration two-component sensor histidine kinase ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.815
rcsC
Two-component system sensor histidine kinase/response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 
 
 0.638
sirA
DNA-binding response regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.633
AIR01131.1
Two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.629
AIR01132.1
Nitrate/nitrite two-component system sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.507
Your Current Organism:
Pluralibacter gergoviae
NCBI taxonomy Id: 61647
Other names: ATCC 33028, CCUG 14557, CDC 604-77, CIP 76.01, CIP 76.1, DSM 9245, Enterobacter gergoviae, Enterobacter gergoviensis, LMG 5739, LMG:5739, NBRC 105706, NCTC 11434, P. gergoviae
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