Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ytfEIron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. (221 aa)    
Predicted Functional Partners:
hmp
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
  
  
 0.965
AIR02074.1
NADH oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.767
AIR02467.1
Hybrid-cluster NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.660
AIR00166.1
Detoxifies nitric oxide using NADH; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.633
AIQ99688.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.610
benC
NADH oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.581
AIR01640.1
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.581
nsrR
Transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.
  
  
 0.531
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.519
AIR01310.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
   
 0.490
Your Current Organism:
Pluralibacter gergoviae
NCBI taxonomy Id: 61647
Other names: ATCC 33028, CCUG 14557, CDC 604-77, CIP 76.01, CIP 76.1, DSM 9245, Enterobacter gergoviae, Enterobacter gergoviensis, LMG 5739, LMG:5739, NBRC 105706, NCTC 11434, P. gergoviae
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