Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL10624.1Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. (916 aa)    
Predicted Functional Partners:
AKL11941.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.920
AKL10567.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.916
AKL15144.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.843
AKL14935.1
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.754
AKL10566.1
Oxygen sensor protein DosP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.664
AKL12511.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    0.644
sirA
Response regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.629
AKL14887.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.610
AKL12347.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    0.572
rumA
23S rRNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
       0.559
Your Current Organism:
Kluyvera intermedia
NCBI taxonomy Id: 61648
Other names: ATCC 33110, CCUG 14183, CIP 79.27, CUETM 77-130, DSM 4581, Enterobacter intermedium, Enterobacter intermedius, Enterobacter intrermedium, K. intermedia, Kluyvera cochleae, LMG 2785, LMG:2785, NBRC 102594, NCTC 12125, strain Gavini E 86
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