node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKL11027.1 | AKL11028.1 | AB182_06780 | AB182_06785 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
AKL11027.1 | AKL11029.1 | AB182_06780 | AB182_06790 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.581 |
AKL11027.1 | purF | AB182_06780 | AB182_06795 | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.762 |
AKL11028.1 | AKL11027.1 | AB182_06785 | AB182_06780 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.930 |
AKL11028.1 | AKL11029.1 | AB182_06785 | AB182_06790 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.712 |
AKL11028.1 | ftsQ | AB182_06785 | AB182_21245 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.747 |
AKL11028.1 | metJ | AB182_06785 | AB182_24515 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.417 |
AKL11028.1 | purF | AB182_06785 | AB182_06795 | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.594 |
AKL11029.1 | AKL11027.1 | AB182_06790 | AB182_06780 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. | 0.581 |
AKL11029.1 | AKL11028.1 | AB182_06790 | AB182_06785 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.712 |
AKL11029.1 | ftsQ | AB182_06790 | AB182_21245 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.606 |
AKL11029.1 | metJ | AB182_06790 | AB182_24515 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.651 |
AKL11029.1 | purC | AB182_06790 | AB182_06180 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.798 |
AKL11029.1 | purE | AB182_06790 | AB182_19375 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.663 |
AKL11029.1 | purF | AB182_06790 | AB182_06795 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.983 |
AKL11029.1 | purM | AB182_06790 | AB182_06065 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazole synthetase; Catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
AKL11029.1 | ygfZ | AB182_06790 | AB182_03830 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Global regulator; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.587 |
AKL11029.1 | zapA | AB182_06790 | AB182_03765 | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | Z-ring-associated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.632 |
ftsQ | AKL11028.1 | AB182_21245 | AB182_06785 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
ftsQ | AKL11029.1 | AB182_21245 | AB182_06790 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Membrane protein required for colicin V production; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.606 |