Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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Textmining
[Homology]
Score
sbmCDNA gyrase inhibitor; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell. (157 aa)    
Predicted Functional Partners:
AKL11268.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.834
AKL12976.1
acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.632
AKL11225.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.586
AKL14323.1
Aldolase; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family.
  
     0.580
AKL12043.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.574
AKL13074.1
Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RNase T2 family.
  
     0.564
AKL14634.1
Cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.554
AKL11266.1
D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
     
 0.526
AKL12541.1
Pentapeptide repeat; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.521
AKL10968.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.485
Your Current Organism:
Kluyvera intermedia
NCBI taxonomy Id: 61648
Other names: ATCC 33110, CCUG 14183, CIP 79.27, CUETM 77-130, DSM 4581, Enterobacter intermedium, Enterobacter intermedius, Enterobacter intrermedium, K. intermedia, Kluyvera cochleae, LMG 2785, LMG:2785, NBRC 102594, NCTC 12125, strain Gavini E 86
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