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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKL13392.1Positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (105 aa)    
Predicted Functional Partners:
GrxD_2
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.999
AKL11197.1
Antiporter; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
     
 0.807
AKL11222.1
Tyrosine protein kinase; Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.807
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.558
AKL13393.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
AKL10501.1
2-octaprenyl-6-methoxyphenyl hydroxylase; Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.523
ampG
Muropeptide transporter; In Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.508
ubiF
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.486
AKL14540.1
Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 
 0.477
AKL10502.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.471
Your Current Organism:
Kluyvera intermedia
NCBI taxonomy Id: 61648
Other names: ATCC 33110, CCUG 14183, CIP 79.27, CUETM 77-130, DSM 4581, Enterobacter intermedium, Enterobacter intermedius, Enterobacter intrermedium, K. intermedia, Kluyvera cochleae, LMG 2785, LMG:2785, NBRC 102594, NCTC 12125, strain Gavini E 86
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