Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
panFSodium/panthothenate symporter; Mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (483 aa)    
Predicted Functional Partners:
AKL14893.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.941
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
      0.940
fis
Fis family transcriptional regulator; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
      0.836
dusB
tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.
      0.801
AccC_1
acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
  
 0.760
putA
Transcriptional regulator; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
  
 0.688
AKL13747.1
Sodium:alanine symporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.631
AKL12790.1
Amino acid:proton symporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.629
AKL14935.1
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.525
caiT
L-carnitine/gamma-butyrobetaine antiporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines.
 
  
 0.523
Your Current Organism:
Kluyvera intermedia
NCBI taxonomy Id: 61648
Other names: ATCC 33110, CCUG 14183, CIP 79.27, CUETM 77-130, DSM 4581, Enterobacter intermedium, Enterobacter intermedius, Enterobacter intrermedium, K. intermedia, Kluyvera cochleae, LMG 2785, LMG:2785, NBRC 102594, NCTC 12125, strain Gavini E 86
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.