node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt_2 | gmk | AXX16_4044 | AXX16_0605 | Adenine phosphoribosyltransferase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.952 |
apt_2 | gpt | AXX16_4044 | AXX16_4189 | Adenine phosphoribosyltransferase. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.936 |
apt_2 | guaA_1 | AXX16_4044 | AXX16_1712 | Adenine phosphoribosyltransferase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.987 |
apt_2 | guaC | AXX16_4044 | AXX16_4374 | Adenine phosphoribosyltransferase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.925 |
apt_2 | purL_2 | AXX16_4044 | AXX16_1668 | Adenine phosphoribosyltransferase. | Phosphoribosylformylglycinamidine synthase, synthetase subunit. | 0.740 |
argS | gmk | AXX16_2580 | AXX16_0605 | Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.493 |
argS | guaA_1 | AXX16_2580 | AXX16_1712 | Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.981 |
argS | purL_2 | AXX16_2580 | AXX16_1668 | Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phosphoribosylformylglycinamidine synthase, synthetase subunit. | 0.622 |
argS | rplA | AXX16_2580 | AXX16_0266 | Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | LSU ribosomal protein L1p (L10Ae); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.528 |
argS | rplK | AXX16_2580 | AXX16_0267 | Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.563 |
gmk | apt_2 | AXX16_0605 | AXX16_4044 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase. | 0.952 |
gmk | argS | AXX16_0605 | AXX16_2580 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.493 |
gmk | gpt | AXX16_0605 | AXX16_4189 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.952 |
gmk | guaA_1 | AXX16_0605 | AXX16_1712 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.963 |
gmk | guaC | AXX16_0605 | AXX16_4374 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.918 |
gmk | purL_2 | AXX16_0605 | AXX16_1668 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Phosphoribosylformylglycinamidine synthase, synthetase subunit. | 0.742 |
gmk | rdgB | AXX16_0605 | AXX16_1314 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.434 |
gpt | apt_2 | AXX16_4189 | AXX16_4044 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Adenine phosphoribosyltransferase. | 0.936 |
gpt | gmk | AXX16_4189 | AXX16_0605 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.952 |
gpt | guaA_1 | AXX16_4189 | AXX16_1712 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.987 |