STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lptDOuter membrane protein Imp, required for envelope biogenesis; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (788 aa)    
Predicted Functional Partners:
lptE
LPS-assembly lipoprotein RlpB precursor (Rare lipoprotein B); Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.
 
 
 
 0.930
lptA
LptA, protein essential for LPS transport across the periplasm; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
 
 
 0.897
surA_2
Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA).
 
  
 0.873
lptF_2
Putative permease.
 
  
 0.850
yaeT
Outer membrane protein assembly factor YaeT precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
  
  
 0.833
yfiO
Putative component of the lipoprotein assembly complex (forms a complex with YaeT, YfgL, and NlpB); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.
 
  
 0.811
lolA
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
   
 0.796
lptC
Uncharacterized protein YrbK; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
 
  
 0.788
apaH
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
 
    0.748
ftsQ
Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
   
 0.745
Your Current Organism:
Serratia rubidaea
NCBI taxonomy Id: 61652
Other names: ATCC 27593, CCUG 10981, CCUG 9286, CIP 103234, DSM 4480, LMG 5019, LMG:5019, NBRC 103169, NCTC 12971, S. rubidaea, Serratia marinorubra, Serratia sp. V1E5a
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