STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpRTranscriptional repressor protein TrpR; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (113 aa)    
Predicted Functional Partners:
AML56086.1
Putative inner membrane protein.
  
    0.780
matP_2
Macrodomain Ter protein YcbG; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.772
lepB_2
Signal peptidase I; Belongs to the peptidase S26 family.
   
    0.770
ycdY
Putative oxidoreductase component of anaerobic dehydrogenases.
  
    0.756
slt
Soluble lytic murein transglycosylase precursor.
 
     0.736
AML58127.1
Hypothetical protein.
  
     0.713
mukE
Chromosome partition protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.692
AML57015.1
Uncharacterized protein YggN.
  
     0.685
mukF
Chromosome partition protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.684
AML58872.1
Putative membrane protein.
  
     0.681
Your Current Organism:
Serratia rubidaea
NCBI taxonomy Id: 61652
Other names: ATCC 27593, CCUG 10981, CCUG 9286, CIP 103234, DSM 4480, LMG 5019, LMG:5019, NBRC 103169, NCTC 12971, S. rubidaea, Serratia marinorubra, Serratia sp. V1E5a
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.