STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRO03601.1SAM-dependent methyltransferase. (382 aa)    
Predicted Functional Partners:
KRO03602.1
Signal transduction histidine kinase.
       0.594
KRO03603.1
DNA-binding response regulator.
       0.594
KRO03600.1
Glucose uptake permease.
 
     0.533
KRO04212.1
dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
    
  0.529
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.508
KRO04407.1
16S rRNA pseudouridylate synthase.
 
 
   0.505
folD
5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
  0.499
KRO04302.1
Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
  
 
  0.472
KRO01727.1
16S rRNA pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family.
   
   0.436
KRO04437.1
tRNA and rRNA cytosine-C5-methylase.
  
  
 0.430
Your Current Organism:
Lactobacillus paucivorans
NCBI taxonomy Id: 616990
Other names: DSM 22467, JCM 18045, L. paucivorans, LMG 25291, LMG:25291, Lactobacillus paucivorans Ehrmann et al. 2010
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