STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRO00624.1Glutathione reductase. (444 aa)    
Predicted Functional Partners:
KRO04922.1
Acetoin pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase.
 0.988
KRO04921.1
Acetoin dehydrogenase complex, E1 component, beta subunit.
 
 0.983
pdhA
Acetoin dehydrogenase complex, E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 
 0.923
KRO04782.1
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.884
KRO04400.1
Thiol-disulfide isomerase and thioredoxin.
  
 0.879
KRN97723.1
Glycine cleavage system H protein (lipoate-binding).
 
  
 0.867
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.836
KRO04346.1
Glutamine synthetase.
  
 
 0.833
KRO03569.1
Glycine cleavage system H protein (lipoate-binding).
    
 0.817
KRO03525.1
Thioredoxin reductase.
 
 0.718
Your Current Organism:
Lactobacillus paucivorans
NCBI taxonomy Id: 616990
Other names: DSM 22467, JCM 18045, L. paucivorans, LMG 25291, LMG:25291, Lactobacillus paucivorans Ehrmann et al. 2010
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