node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRN97782.1 | KRN97866.1 | IV54_GL001082 | IV54_GL001166 | Superfamily I DNA RNA helicase. | Excinuclease subunit A. | 0.520 |
KRN97782.1 | KRN97867.1 | IV54_GL001082 | IV54_GL001167 | Superfamily I DNA RNA helicase. | Superfamily II DNA helicase. | 0.936 |
KRN97782.1 | polA | IV54_GL001082 | IV54_GL001456 | Superfamily I DNA RNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.929 |
KRN97782.1 | uvrB | IV54_GL001082 | IV54_GL000110 | Superfamily I DNA RNA helicase. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.879 |
KRN97782.1 | uvrC | IV54_GL001082 | IV54_GL000671 | Superfamily I DNA RNA helicase. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.593 |
KRN97866.1 | KRN97782.1 | IV54_GL001166 | IV54_GL001082 | Excinuclease subunit A. | Superfamily I DNA RNA helicase. | 0.520 |
KRN97866.1 | KRN97867.1 | IV54_GL001166 | IV54_GL001167 | Excinuclease subunit A. | Superfamily II DNA helicase. | 0.459 |
KRN97866.1 | dnaJ | IV54_GL001166 | IV54_GL000720 | Excinuclease subunit A. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.443 |
KRN97866.1 | mfd | IV54_GL001166 | IV54_GL000259 | Excinuclease subunit A. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.811 |
KRN97866.1 | polA | IV54_GL001166 | IV54_GL001456 | Excinuclease subunit A. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.435 |
KRN97866.1 | uvrB | IV54_GL001166 | IV54_GL000110 | Excinuclease subunit A. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.954 |
KRN97866.1 | uvrC | IV54_GL001166 | IV54_GL000671 | Excinuclease subunit A. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.468 |
KRN97867.1 | KRN97782.1 | IV54_GL001167 | IV54_GL001082 | Superfamily II DNA helicase. | Superfamily I DNA RNA helicase. | 0.936 |
KRN97867.1 | KRN97866.1 | IV54_GL001167 | IV54_GL001166 | Superfamily II DNA helicase. | Excinuclease subunit A. | 0.459 |
KRN97867.1 | polA | IV54_GL001167 | IV54_GL001456 | Superfamily II DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.927 |
dnaJ | KRN97866.1 | IV54_GL000720 | IV54_GL001166 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Excinuclease subunit A. | 0.443 |
dnaJ | polA | IV54_GL000720 | IV54_GL001456 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.716 |
mfd | KRN97866.1 | IV54_GL000259 | IV54_GL001166 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Excinuclease subunit A. | 0.811 |
mfd | polA | IV54_GL000259 | IV54_GL001456 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.800 |
mfd | uvrB | IV54_GL000259 | IV54_GL000110 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.558 |