KRO03667.1 protein (Lactobacillus paucivorans)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

KRO03667.1

HAD superfamily hydrolase. (274 aa)

Predicted Functional Partners:

KRO03664.1

0.844

KRO03393.1

0.808

KRO00272.1

0.703

KRO04438.1

0.660

KRO03666.1

0.653

KRO05615.1

0.546

KRO03665.1

0.505

KRO03394.1

0.469

KRO03668.1

0.464

KRO04990.1

0.459

Your Current Organism:

Lactobacillus paucivorans

NCBI taxonomy Id: 616990
Other names: DSM 22467, JCM 18045, L. paucivorans, LMG 25291, LMG:25291, Lactobacillus paucivorans Ehrmann et al. 2010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KRO00272.1	KRO03664.1	IV54_GL000595	IV54_GL002125	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.471
KRO00272.1	KRO03667.1	IV54_GL000595	IV54_GL002128	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.703
KRO00272.1	KRO04438.1	IV54_GL000595	IV54_GL001362	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.702
KRO03393.1	KRO03394.1	IV54_GL000299	IV54_GL000300	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.688
KRO03393.1	KRO03664.1	IV54_GL000299	IV54_GL002125	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.461
KRO03393.1	KRO03667.1	IV54_GL000299	IV54_GL002128	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.808
KRO03393.1	KRO04438.1	IV54_GL000299	IV54_GL001362	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.518
KRO03393.1	KRO04990.1	IV54_GL000299	IV54_GL000716	HAD superfamily hydrolase.	FAD synthase; Belongs to the ribF family.	0.492
KRO03394.1	KRO03393.1	IV54_GL000300	IV54_GL000299	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.688
KRO03394.1	KRO03664.1	IV54_GL000300	IV54_GL002125	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.469
KRO03394.1	KRO03667.1	IV54_GL000300	IV54_GL002128	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.469
KRO03394.1	KRO04438.1	IV54_GL000300	IV54_GL001362	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.519
KRO03394.1	KRO04990.1	IV54_GL000300	IV54_GL000716	HAD superfamily hydrolase.	FAD synthase; Belongs to the ribF family.	0.492
KRO03664.1	KRO00272.1	IV54_GL002125	IV54_GL000595	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.471
KRO03664.1	KRO03393.1	IV54_GL002125	IV54_GL000299	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.461
KRO03664.1	KRO03394.1	IV54_GL002125	IV54_GL000300	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.469
KRO03664.1	KRO03665.1	IV54_GL002125	IV54_GL002126	HAD superfamily hydrolase.	Alpha beta hydrolase.	0.574
KRO03664.1	KRO03666.1	IV54_GL002125	IV54_GL002127	HAD superfamily hydrolase.	Cellobiose-specific PTS system IIC component.	0.512
KRO03664.1	KRO03667.1	IV54_GL002125	IV54_GL002128	HAD superfamily hydrolase.	HAD superfamily hydrolase.	0.844
KRO03664.1	KRO04990.1	IV54_GL002125	IV54_GL000716	HAD superfamily hydrolase.	FAD synthase; Belongs to the ribF family.	0.474

page 1 of 3

Network Stats

number of nodes:

7

number of edges:

10

average node degree:

2.86

avg. local clustering coefficient:

0.895

expected number of edges:

7

PPI enrichment p-value:

0.212

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006548

Histidine catabolic process

4 of 5

2.43

2.77

5.24e-06

GO:0006547

Histidine metabolic process

5 of 20

1.93

2.45

5.24e-06

GO:0019557

Histidine catabolic process to glutamate and formate

3 of 4

2.41

1.89

0.00029

GO:0019556

Histidine catabolic process to glutamate and formamide

3 of 4

2.41

1.89

0.00029

GO:1901565

Organonitrogen compound catabolic process

5 of 94

1.26

1.11

0.00080

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5764

Histidine metabolism, and UbiC transcription regulator-associated

6 of 6

2.53

5.24

4.78e-11

CL:5730

Mixed, incl. Glycine betaine transport, and Histidine catabolic process

8 of 24

2.05

4.91

1.54e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00340

Histidine metabolism

6 of 28

1.86

3.2

1.86e-08

map01100

Metabolic pathways

10 of 1328

0.41

0.31

0.0146

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0369

Histidine metabolism

3 of 3

2.53

2.19

8.41e-05

KW-0660

Purine salvage

2 of 4

2.23

1.01

0.0131

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF05013

N-formylglutamate amidohydrolase

2 of 3

2.35

0.74

0.0454

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