node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_000733925_02079 | GCA_000733925_02372 | GCA_000733925_02079 | GCA_000733925_02372 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.516 |
GCA_000733925_02079 | GCA_000733925_02792 | GCA_000733925_02079 | GCA_000733925_02792 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.771 |
GCA_000733925_02079 | GCA_000733925_02793 | GCA_000733925_02079 | GCA_000733925_02793 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.838 |
GCA_000733925_02079 | ilvB | GCA_000733925_02079 | GCA_000733925_02363 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein. | 0.900 |
GCA_000733925_02079 | ilvC | GCA_000733925_02079 | GCA_000733925_02365 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.777 |
GCA_000733925_02079 | ilvH | GCA_000733925_02079 | GCA_000733925_02364 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein. | 0.809 |
GCA_000733925_02079 | leuB | GCA_000733925_02079 | GCA_000733925_02371 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.803 |
GCA_000733925_02079 | leuC | GCA_000733925_02079 | GCA_000733925_02374 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.854 |
GCA_000733925_02079 | leuD | GCA_000733925_02079 | GCA_000733925_02373 | Unannotated protein; Belongs to the IlvD/Edd family. | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.803 |
GCA_000733925_02372 | GCA_000733925_02079 | GCA_000733925_02372 | GCA_000733925_02079 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Belongs to the IlvD/Edd family. | 0.516 |
GCA_000733925_02372 | GCA_000733925_02792 | GCA_000733925_02372 | GCA_000733925_02792 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.895 |
GCA_000733925_02372 | GCA_000733925_02793 | GCA_000733925_02372 | GCA_000733925_02793 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.760 |
GCA_000733925_02372 | ilvB | GCA_000733925_02372 | GCA_000733925_02363 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein. | 0.955 |
GCA_000733925_02372 | ilvC | GCA_000733925_02372 | GCA_000733925_02365 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.717 |
GCA_000733925_02372 | ilvD | GCA_000733925_02372 | GCA_000733925_02362 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Belongs to the IlvD/Edd family. | 0.778 |
GCA_000733925_02372 | ilvH | GCA_000733925_02372 | GCA_000733925_02364 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein. | 0.960 |
GCA_000733925_02372 | leuB | GCA_000733925_02372 | GCA_000733925_02371 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.941 |
GCA_000733925_02372 | leuC | GCA_000733925_02372 | GCA_000733925_02374 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.989 |
GCA_000733925_02372 | leuD | GCA_000733925_02372 | GCA_000733925_02373 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.994 |
GCA_000733925_02792 | GCA_000733925_02079 | GCA_000733925_02792 | GCA_000733925_02079 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Unannotated protein; Belongs to the IlvD/Edd family. | 0.771 |