STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDB09292.1Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (748 aa)    
Predicted Functional Partners:
SDB57353.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 
 0.977
SDB13645.1
2-oxoglutarate ferredoxin oxidoreductase subunit delta.
  
 
 0.948
SDB13691.1
2-oxoglutarate ferredoxin oxidoreductase, gamma subunit.
  
 
 0.946
SDB21181.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.937
SDB13662.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.927
SDB16825.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.927
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
  
 0.921
SDB32037.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.824
SDB14312.1
NADPH-dependent glutamate synthase beta chain.
   
 
 0.778
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
  
 0.769
Your Current Organism:
Desulfonatronum thiosulfatophilum
NCBI taxonomy Id: 617002
Other names: D. thiosulfatophilum, DSM 21338, Desulfonatronum sp. AHT30, Desulfonatronum sp. ASO4-2, Desulfonatronum thiosulfatophilum Sorokin et al. 2011, UNIQEM U757, strain ASO4-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.