Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000000041Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (903 aa)    
Predicted Functional Partners:
ENSACIP00000027637
MYC binding protein 2.
    
 0.976
ENSACIP00000009916
Mitogen-activated protein kinase kinase 7.
    
 0.938
MAP3K13
Mitogen-activated protein kinase kinase kinase.
     
  0.865
MAP3K12
Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.
     
  0.865
ENSACIP00000020344
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
     
 0.798
ENSACIP00000014779
FRA10A associated CGG repeat 1.
    
   0.544
CDC25B
Cell division cycle 25B.
   
  
 0.528
ENSACIP00000027422
F-box protein 45.
    
 
 0.504
ENSACIP00000000974
Mitogen-activated protein kinase 8 interacting protein 2.
    
 
 0.503
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 
 0.503
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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