Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000000056Small integral membrane protein 29. (94 aa)    
Predicted Functional Partners:
ENSACIP00000004168
Mitotic arrest deficient 2 like 2.
    
   0.426
ENSACIP00000021506
Transforming growth factor, alpha.
     
  0.411
ENSACIP00000002580
TGF_BETA_2 domain-containing protein.
    
 0.406
ENSACIP00000002598
Growth differentiation factor 6a.
    
 0.406
ENSACIP00000002636
Bone morphogenetic protein 3; Belongs to the TGF-beta family.
    
 0.406
ENSACIP00000002991
TGFb_propeptide domain-containing protein.
    
 0.406
ENSACIP00000003162
Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family.
    
 0.406
ENSACIP00000003479
Growth differentiation factor 11.
    
 0.406
ENSACIP00000004107
Bone morphogenetic protein 7b.
    
 0.406
ENSACIP00000004916
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.406
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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