Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000000071Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family. (219 aa)    
Predicted Functional Partners:
NCBP1
Nuclear cap binding protein subunit 1.
    
 0.909
ENSACIP00000015637
Eukaryotic translation initiation factor 4 gamma, 3a.
   
 0.907
ENSACIP00000019038
Uncharacterized protein.
   
 0.885
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1.
   
 0.885
ENSACIP00000012828
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
 0.880
ENSACIP00000000258
Eukaryotic translation initiation factor 4, gamma 2a.
   
 0.878
ENSACIP00000009926
Eukaryotic translation initiation factor 4, gamma 2b.
   
 0.878
ENSACIP00000011009
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
    
0.870
ENSACIP00000011919
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
    
0.870
ENSACIP00000016185
MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily.
    
 0.833
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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