Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
ENSACIP00000000098Retrotrans_gag domain-containing protein. (340 aa)    
Predicted Functional Partners:
ENSACIP00000006898
ERCC4 domain-containing protein.
    
 0.820
ENSACIP00000006969
Uncharacterized protein.
    
 0.820
ENSACIP00000011559
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
     
 0.728
ENSACIP00000007680
Lin-54 DREAM MuvB core complex component.
    
 0.557
ENSACIP00000011375
Lin-52 DREAM MuvB core complex component.
    
 0.557
ENSACIP00000007311
Lin-9 DREAM MuvB core complex component.
    
 0.540
ENSACIP00000018368
Mindbomb E3 ubiquitin protein ligase 2.
    
  0.532
ENSACIP00000004881
Methionine sulfoxide reductase B1b.
    
 0.529
ENSACIP00000009319
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.529
ENSACIP00000016564
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.529
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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