Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP000000010496-pyruvoyl tetrahydrobiopterin synthase. (148 aa)    
Predicted Functional Partners:
ENSACIP00000010595
Sepiapterin reductase b.
    
 0.977
ENSACIP00000004170
GTP cyclohydrolase 2.
  
 
 0.958
ENSACIP00000027756
GTP cyclohydrolase 1.
  
 
 0.958
ENSACIP00000018123
GTP cyclohydrolase I feedback regulator.
     
 0.895
CBR1
Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.879
ENSACIP00000020206
Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.879
ENSACIP00000020231
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.879
ENSACIP00000024852
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2.
    
 0.871
ENSACIP00000024868
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1.
    
 0.871
ENSACIP00000016533
Uncharacterized protein.
     
  0.859
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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