Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001060Elongin C paralog a; Belongs to the SKP1 family. (110 aa)    
Predicted Functional Partners:
ENSACIP00000012470
Ring-box 1, E3 ubiquitin protein ligase.
   
 0.999
ENSACIP00000015728
Ring finger protein 7.
   
 0.999
ENSACIP00000018421
UBX domain-containing protein 7.
   
 0.999
ENSACIP00000029344
Von Hippel-Lindau tumor suppressor.
   
 0.999
ENSACIP00000008651
Elongin B.
   
 0.997
ENSACIP00000018354
Ubiquitin-like domain-containing protein.
   
 0.997
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.995
ENSACIP00000022008
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.995
ENSACIP00000012506
Suppressor of cytokine signaling 2.
    
 0.994
ENSACIP00000031374
Cullin 2; Belongs to the cullin family.
   
 0.994
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
Server load: low (36%) [HD]