Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000001078Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (693 aa)    
Predicted Functional Partners:
ENSACIP00000001813
NDK domain-containing protein.
   
 
 0.749
ENSACIP00000029324
Uncharacterized protein.
    
 0.677
ENSACIP00000029330
WD_REPEATS_REGION domain-containing protein.
    
 0.677
ENSACIP00000025650
Leucine-rich repeats and guanylate kinase domain containing.
    
 
 0.672
ENSACIP00000003133
Uncharacterized protein.
   
 0.613
ENSACIP00000019456
RAB guanine nucleotide exchange factor (GEF) 1, like.
   
 0.613
ENSACIP00000020986
RAB guanine nucleotide exchange factor (GEF) 1.
   
 0.613
ENSACIP00000012327
DUF4201 domain-containing protein.
   
   0.564
ENSACIP00000021947
PARK2 co-regulated.
   
 
 0.564
ENSACIP00000003360
Uncharacterized protein.
   
   0.563
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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