Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000001085AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (167 aa)    
Predicted Functional Partners:
ENSACIP00000001911
AP-1 complex subunit gamma.
    
 0.978
ENSACIP00000007609
AP-1 complex subunit gamma.
    
 0.966
ENSACIP00000013889
AP complex subunit beta.
    
 0.959
ENSACIP00000004103
AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
   
 0.957
ENSACIP00000010364
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 0.940
ENSACIP00000014802
Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.
    
 0.940
ENSACIP00000007977
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 0.922
ENSACIP00000019762
AP complex subunit beta.
    
 0.922
ENSACIP00000025034
AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]
    
 0.899
ENSACIP00000018891
AP4E_app_platf domain-containing protein.
    
 0.822
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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