STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001101Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1816 aa)    
Predicted Functional Partners:
TARBP2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.993
ENSACIP00000026006
Protein kinase, interferon-inducible double stranded RNA dependent activator.
    
 0.993
ENSACIP00000025971
DGCR8 microprocessor complex subunit.
    
 0.984
ENSACIP00000001006
Staufen double-stranded RNA binding protein 2.
    
 0.932
ENSACIP00000020515
Staufen double-stranded RNA binding protein 1.
    
 0.932
ENSACIP00000025089
Piwi-like RNA-mediated gene silencing 2; Belongs to the argonaute family.
    
 
 0.927
XPO5
Exportin 5.
    
 0.918
ENSACIP00000001460
Argonaute RISC catalytic component 2; Belongs to the argonaute family.
   
 0.917
ENSACIP00000006715
ArgoN domain-containing protein.
   
 0.917
ENSACIP00000006752
Argonaute RISC component 1; Belongs to the argonaute family.
   
 0.917
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.