Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000001146Uncharacterized protein. (489 aa)    
Predicted Functional Partners:
ENSACIP00000012507
Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
   
 0.779
ENSACIP00000013171
Peroxisome proliferator-activated receptor gamma, coactivator 1 beta.
    
 0.745
ENSACIP00000006804
Nuclear receptor interacting protein 1b.
    
 0.696
ENSACIP00000030057
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.660
ENSACIP00000017661
Myb-like, SWIRM and MPN domains 1.
    
  0.656
ENSACIP00000013570
Nuclear receptor subfamily 0, group B, member 2a.
    
 0.604
ENSACIP00000031671
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.603
ENSACIP00000010025
Ras association domain family member 9.
      
 0.599
ENSACIP00000004941
Deacetylase sirtuin-type domain-containing protein.
    
 0.594
ENSACIP00000009511
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1.
    
  0.590
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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