Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACIP00000001174DED domain-containing protein. (160 aa)    
Predicted Functional Partners:
ENSACIP00000003684
Tnfrsf1a-associated via death domain.
   
 0.990
ENSACIP00000002642
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.989
ENSACIP00000022385
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.987
ENSACIP00000011777
Receptor-interacting serine-threonine kinase 3.
   
 0.986
CASP6
Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
   
 0.981
ENSACIP00000028405
PYD and CARD domain containing.
   
 0.979
ENSACIP00000029991
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.979
ENSACIP00000010053
Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.
    
 0.971
ENSACIP00000011334
X-linked inhibitor of apoptosis.
   
 0.965
ENSACIP00000020344
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.964
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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