Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001177alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (438 aa)    
Predicted Functional Partners:
ENSACIP00000028722
Glucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family.
   
 
 0.924
ENSACIP00000004280
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
 0.912
ENSACIP00000009090
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
 0.912
ENSACIP00000022451
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
 0.912
ENSACIP00000026742
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
     
  0.865
ENSACIP00000005727
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase b.
     
 0.808
ENSACIP00000028138
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a.
     
 0.808
ENSACIP00000003495
Mannosidase, alpha, class 2C, member 1.
   
  
 0.651
ENSACIP00000016794
Homeobox protein.
      
 0.641
ENSACIP00000017840
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
   
 
 0.640
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.