Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000001208Splicing factor proline/glutamine-rich. (606 aa)    
Predicted Functional Partners:
ENSACIP00000003548
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 
 0.828
ENSACIP00000031479
CDC5 cell division cycle 5-like (S. pombe).
   
 
 0.779
ENSACIP00000007340
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 
 0.751
ENSACIP00000018190
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
   
 
 0.751
ENSACIP00000010990
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
   
 
 0.739
RANBP2
RAN binding protein 2.
   
 
 0.720
ENSACIP00000002105
GTP binding protein 6 (putative).
    
   0.715
ENSACIP00000015424
Heterogeneous nuclear ribonucleoprotein M.
   
 
 0.675
ENSACIP00000021220
DEAH (Asp-Glu-Ala-His) box helicase 9.
   
 
 0.671
ENSACIP00000027167
Zinc finger CCCH-type containing 18.
   
   0.636
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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