Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001218Ecm29 proteasome adaptor and scaffold. (1813 aa)    
Predicted Functional Partners:
ENSACIP00000011922
Adhesion regulating molecule 1.
    
 
 0.978
ENSACIP00000017184
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
    
 
 0.966
ENSACIP00000009760
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
   
 
 0.962
ENSACIP00000024559
Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.
   
 
 0.956
ENSACIP00000025192
Ubiquitin carboxyl-terminal hydrolase.
   
 
 0.956
ENSACIP00000000148
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.954
ENSACIP00000017546
Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.
   
 
 0.950
ENSACIP00000019808
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
 
 0.950
ENSACIP00000011315
Proteasome 26S subunit, non-ATPase 6.
   
 
 0.946
ENSACIP00000016488
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
 
 0.942
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
Server load: low (22%) [HD]