Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (178 aa)    
Predicted Functional Partners:
ENSACIP00000023657
Occludin a.
     
 0.922
ENSACIP00000007314
Tight junction protein 1a; Belongs to the MAGUK family.
    
 0.897
ENSACIP00000020654
Tight junction protein 1b; Belongs to the MAGUK family.
    
 0.897
ENSACIP00000003288
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
     
 0.878
ENSACIP00000007802
Claudin 11a.
     
 0.878
ENSACIP00000024023
Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family.
    
 0.878
ENSACIP00000000280
Par-3 family cell polarity regulator alpha, b.
     
 0.875
PARD3
Par-3 family cell polarity regulator.
     
 0.875
ENSACIP00000000342
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
     
 0.872
ENSACIP00000001740
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
     
 0.872
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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